Exenatide synthesis, pharmacology
Biguanide class, sulphur urea class, alpha - dissertation+definition inhibitor, 2,4-thiazolidinedione and insulin and so on. Approved, Investigational Lipoic Acid may increase the hypoglycemic activities of Exenatide.
Investigational, Withdrawn The therapeutic efficacy of Exenatide can be decreased when used in combination with Chlorthalidone. Exenatide also suppresses pancreatic release of glucagon in response to eating, which helps stop the synthesis from overproducing sugar when it is unneeded, which prevents hyperglycemia high blood sugar levels.
Experimental The serum concentration of Drospirenone can be decreased when it is combined with Exenatide. However, diabetics do have a greater incidence of pancreatitis than do non-diabetics. Eli Lilly has stated the drug causes an increase in thyroid problems in rats given high doses. Approved Exenatide may increase the anticoagulant activities of Clorindione.
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